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30,000+ customers. 700+ verified reviews. 4.7 stars.

My ALT Was 67. My Doctor Said "Just Watch It." 8 Months Later I Was Still Bloated, Exhausted, and 14 Pounds Heavier.

Nobody told me it was my liver running all of it. One organ. Five systems. When it slowed down, everything broke in sequence.

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$1.31/day | 60-Day Money-Back Guarantee | Free Shipping

Couple in their 50s holding AlphaCleanse bottles
🫀 Liver
🌿 Digestion
Skin
Energy
Weight
🌜 Sleep
Gail P.
Gail P., 65+
Week 2
"After only 2 weeks of using Alpha Cleanse I have noticed less bloating, better sleep and I'm a couple of lbs down."
Jeff S.
Jeff S., 55-64
Month 1
"My skin itching all but stopped. I was very skeptical but my wife convinced me to try it. Best decision we made."
JoLen B.
JoLen B., 65+
Month 2
"I have had so much more energy and the bloating has reduced significantly. I feel like a different person."
Made with Organic Ingredients No Proprietary Blends 27 PubMed Citations

How Fast Does The Cascade Start?

Real timelines from verified customers.

Day 1-3
"Nearly instant stopping of itching was life-changing."
- Patrick H.
Day 5
"Abdominal bloating and itching gone."
- Alita S.
Week 2
"Less bloated, more energy, couple pounds down."
- Anne T.
Month 1
"Liver enzymes went to better than normal."
- Jeffery C.
Month 3
"ALT dropped from 160 to 60. AST dropped from 77 to 35."
- Chris M.

Why Fixing Your Liver Fixes Everything Else

Your liver is not just a filter. It is the control room for 5 body systems. When it slows down, everything downstream breaks. When it speeds back up, everything downstream recovers. That is The Liver Cascade Effect.

Woman in her 50s at kitchen table dealing with morning bloating, AlphaCleanse bottle nearby

You cut the carbs. The bloating stayed. You tried milk thistle. Your numbers did not move. You blamed your age. Nothing lined up.

It was never 5 separate problems. It was 1 organ, showing up in 5 places.

Your liver runs 500+ functions simultaneously. Bile for digestion. Hormone clearance. Fat conversion. Toxin processing. When the workload exceeds capacity, it triages. It keeps you alive and deprioritizes everything else.

You do not feel your liver struggling. You feel the cascade of everything it stopped doing:

Bloating = reduced bile
Fatigue = erratic glucose
Belly fat = overflow storage
Itching = histamine backup

This is The Liver Cascade Effect. It works in both directions. When the liver slows, everything breaks in sequence. When you restore it, everything recovers in the same sequence.

Human torso with liver highlighted and connections to five body systems

Here is what that looks like, system by system:

The Liver Cascade Effect: liver connected to digestion, skin, energy, weight, and sleep
1
First Domino: Digestion

The problem:

Your liver produces bile to break down fat. When overloaded, bile production drops. Undigested fat ferments in your gut. Gas, bloating, distension. Worse after every meal.

Elimination diets will not fix this. The issue is not what you eat. It is that your liver cannot produce enough bile to process it.

When bile restores:

Bloating resolves within 1-2 weeks. First improvement most customers notice.

🌿
Bile Production
500-600ml/day when healthy.
First function to recover.
"I was bloated nearly every day. I'm nearly one month in and the bloating is much less."
- Stacey M., 45-54, Verified Buyer
"Within a couple weeks my bloating and gas is gone."
- Gina L., 55-64, Verified Buyer
2
Second Domino: Skin

The problem:

Your liver clears histamine and inflammatory compounds. When it falls behind, histamine builds in skin tissue. Result: itching with no visible cause. Dullness no moisturizer fixes. Puffiness that appears overnight.

These are not skin problems. They are liver clearance problems visible on the surface.

When clearance restores:

Histamine clears. Inflammatory markers drop. Skin clarity returns within the first month.

Histamine Clearance
Itching stops first.
Clarity follows in weeks.
"My skin and eyes look clearer, my digestion has improved dramatically."
- Rae B., 55-64, Verified Buyer
"After 6 months I no longer have itchy skin."
- Leah F., 65+, Verified Buyer
3
Third Domino: Energy

The problem:

Your liver stores glucose and releases it as fuel. When overloaded, release becomes erratic. Too much, then not enough. That is the 2-3pm crash no amount of coffee fixes.

It also clears cortisol, thyroid hormones, and insulin. When clearance slows, these accumulate in wrong ratios. Brain fog. Mental sluggishness. A battery that never charges.

When metabolism stabilizes:

Glucose steadies. Hormones clear. Customers call it "brightness." All-day clarity, not a caffeine spike.

Glucose Regulation
Steady release, not spikes.
The crash stops.
"I feel so much brighter when I'm taking AlphaCleanse."
- Jo B., 45-54, Verified Buyer
"Alpha Cleanse has given me my sharp mind back."
- Justin S., Verified Buyer
4
Fourth Domino: Weight

The problem:

Your liver converts stored fat into energy. When overwhelmed, it cannot. Worse, it stores excess toxins inside new fat cells around your midsection.

This is not a discipline problem. Your body resists losing this fat because releasing it would flood your blood with toxins the liver could not handle. Diets and exercise fail because you are fighting a protective mechanism.

When processing restores:

Toxins clear normally. The body releases the protective fat. Midsection weight shifts. Slowest effect (weeks to months), but most dramatic.

Fat Metabolism
Midsection weight is the last
domino, but the biggest.
"Lost nearly 20 pounds in three months. Liver enzymes back to normal."
- Scott D., 55-64, Verified Buyer
"Helping to reduce menopausal weight gain, improving skin tone, energy, sleep."
- Kate F., 55-64, Verified Buyer
5
Fifth Domino: Sleep

The problem:

Your liver keeps blood sugar stable overnight and clears excess cortisol. When overloaded, blood sugar drops mid-sleep. Cortisol spikes. You wake up. Racing mind. Cannot get back to deep sleep.

Your nervous system never fully powers down.

When processing restores:

Blood sugar stays stable. Cortisol clears on schedule. Customers report sleeping through the night for the first time in years.

🌜
Cortisol Clearance
Stable blood sugar.
Deep sleep returns.
"Better sleep and I'm a couple of lbs down. I'll keep using it."
- Gail P., 65+, Verified Buyer
"Sleeping deeper now. More energy during the day."
- Anne T., 65+, Verified Buyer
See the 12 Ingredients That Trigger the Cascade See Pricing

Their Liver Was The First Domino

Notice the pattern: they came for one symptom. They got improvements across multiple systems.

DB
Doug B.
55-64, Male
★★★★★
✓ Verified Purchase
"I have spent $1,000s on other brands and products. This one seems to be working the best. I have been going through liver issues since Oct '24 and have tried many supplements."
Liver Energy
SM
Stacey M.
45-54, Female
★★★★★
✓ Verified Purchase
"I was bloated nearly every day, feeling fatigued and sluggish and really struggling to lose weight. I'm nearly one month in and I can already feel the changes."
Bloating Weight Energy Brain Fog
MB
Michael B.
45-54, Male
★★★★★
✓ Verified Purchase
"Pains where my liver is, itching, bloating. All stopped happening. I now feel amazing."
Liver Pain Itching Bloating Energy
KC
Ken C.
Male
★★★★★
✓ Verified Purchase
"The bloat is gone, itchiness abates tremendously and my brain fog is near gone."
Bloating Itching Brain Fog
KF
Kate F.
55-64, Female
★★★★★
✓ Verified Purchase
"Great for helping to reduce menopausal weight gain, improving skin tone, increasing energy levels, improving sleep patterns."
Weight Skin Energy Sleep
CM
Chris M.
55-64, Male
★★★★★
✓ Verified Purchase
"ALT dropped from 160 to 60. AST dropped from 77 to 35. I also have less bloating."
Liver Enzymes Bloating Labs
Real AlphaCleanse customers holding their bottles - 6 verified Okendo reviews
700+ Verified Reviews 4.7 Star Average 30,000+ Customers
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Why Milk Thistle Alone Is Not Enough

Tried milk thistle? It supports Phase I only. Phase II goes completely unsupported. That is why your numbers did not move.

Phase I: Oxidation
T
t t
Enzymes break toxins into intermediate metabolites. Milk thistle supports this phase.
Intermediates are MORE reactive than the original toxins
Phase II: Conjugation
t t
+
Different enzymes neutralize those intermediates so kidneys can flush them. Requires beetroot, spirulina, turmeric.
Milk thistle accelerates Phase I. Without Phase II support, the broken-apart pieces pile up. That is why you felt nothing, or felt worse.

Then there is absorption. Most supplement ingredients have low bioavailability. Your gut breaks them down before they reach the liver. AlphaCleanse includes BioPerine (black pepper extract), shown to increase bioavailability by up to 2,000%.

Phase I vs Phase II detoxification: single ingredient bottleneck vs full spectrum flow
💊
Single Ingredient

Phase I only (silymarin)

Phase II unsupported

Poor absorption

Intermediate metabolites accumulate. Potentially more harmful than original toxins

🌱
AlphaCleanse (12 Ingredients)

Phase I: Milk Thistle, Schisandra, Reishi

Phase II: Beetroot, Spirulina, Nettle, Turmeric

Absorption: BioPerine (2,000% boost)

Full detox pathway. Break down, conjugate, absorb, eliminate

"I have been going through liver issues since Oct '24 and have tried many supplements. This one seems to be working the best. I have spent $1,000s on other brands."

- Doug B., Verified Buyer

"I tried milk thistle for 3 months with no change. AlphaCleanse brought my ALT back to normal range in 60 days."

- Carolyn P., 55-64, Verified Buyer

The 12 Ingredients Behind The Liver Cascade Effect

No proprietary blends. No hidden doses. Every ingredient, every amount, listed right here.

Flat lay of AlphaCleanse ingredients: turmeric, milk thistle, ginger, beetroot, spirulina, reishi
1
Trigger the Cascade
Liver Boosting
IngredientDoseRole
Milk Thistle165 mgSilymarin protects liver cells, may support regeneration
Dandelion Root55 mgMay stimulate bile production
Schisandra Berry27.5 mgAdaptogen, may support enzyme balance
Reishi Mushroom55 mgMay support immune function, reduce inflammation
2
Sustain the Downstream
Digestion Easing
IngredientDoseRole
Ginger110 mgMay ease nausea, support gut motility
Turmeric110 mgCurcumin may support bile flow
Rhubarb Root27.5 mgGentle digestive support
Burdock Root27.5 mgTraditional digestive tonic
3
Protect the Cascade
Detoxifying + Nourishing
IngredientDoseRole
Spirulina110 mgMay support detox pathways with chlorophyll
Beetroot55 mgBetalains may support Phase 2 detoxification
Nettle Leaf27.5 mgRich in minerals, may reduce inflammation
BioPerine (Black Pepper)2.75 mgIncreases bioavailability by up to 2,000%
This is why our formula absorbs better than standalone supplements.
Couple in their 50s looking at lab results with relief, AlphaCleanse bottle on counter

Still Skeptical? You Should Be.

Most liver supplements are overpriced milk thistle in a fancy bottle. Here is why this one is different.

"I have tried other liver supplements."

Most liver supplements contain 1 ingredient: milk thistle. Milk thistle supports Phase I detoxification. Phase II goes completely unsupported. That is like changing your oil but never changing the filter. AlphaCleanse covers Phase I, Phase II, and absorption with 12 ingredients at disclosed doses.

"It is just another Facebook supplement."

700+ verified reviews on Okendo, an independent third-party platform. Every ingredient and exact dose listed on the label. No proprietary blends. No hidden formulas. And a 60-day money-back guarantee. No questions asked.

"I cannot afford it."

$1.31 per day. That is less than a cup of coffee. Compare that to $4,000 per year in monitoring appointments that measure your decline without reversing it. Or $1,000s on supplements that did not move your numbers. This is the last supplement you will need to try.

"How do I know it will work for me?"

You do not. That is what the 60-day money-back guarantee is for. Try it for 60 days. If you do not feel the difference in your energy and digestion, you get every penny back. No questions asked. We even let you keep the bottle.

Choose Your Supply

Every order includes free shipping and a 60-day money-back guarantee.

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$49/ea
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Total: $39.20
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Alpha Cleanse 3 Bottles
93% of customers who see results choose 3 bottles
only $1.31 a day
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Total: $117.60
Delivery every 90 days
Save 20%  (Total savings: $29.40)
1 FREE Fatty Liver Guide ($39.90 value)
Locked-in pricing — your price never increases
No commitment — pause or skip anytime
Covers the full 3-phase liver regeneration cycle
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Alpha Cleanse 2 Bottles
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60
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60-Day Empty Bottle Guarantee

Try Alpha Cleanse risk-free. Not thrilled? Return even the empty bottles for a 100% refund. No questions asked.

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Why Thousands of Adults 40+ Choose EdenBoost

Transparent labels

Fully Transparent Labels

No proprietary blends. All ingredients and doses clearly listed.

Clinician recommended

Clinician-Recommended

Recommended by 246+ clinicians to their patients. Not compensated.

Science-backed

Science-Backed Formula

Verified for potency and safety by nutritionists and scientists.

Made in USA

Made in the USA

FDA-Registered, cGMP-Certified facility. Microbiology and heavy metal tested.

60-Day Money-Back Guarantee

60-Day Money-Back Guarantee

Try AlphaCleanse for 60 days. If you do not feel the difference in your energy, your digestion, or your clarity, contact us for a full refund. No questions. No hoops. We will even let you keep the bottle.

Try AlphaCleanse Risk-Free
Woman in her late 50s sleeping peacefully, AlphaCleanse bottle on bedside table

What Healthcare Professionals Are Saying

Independent clinician reviews collected by FrontRow Health.

What 700+ Verified Customers Are Saying

These are third party verified reviews from genuine, paying customers who've purchased our products. We collect reviews through Okendo, a third-party review collection service. We do this to ensure that our reviews are authentic and honest.

Common Questions About AlphaCleanse

"Will it work for me?"
1. How long until I notice a difference?
Most customers report noticeable changes within the first 1-2 weeks. Common early improvements include reduced bloating, less itching, and more energy. Deeper changes like improved lab results typically show up after 30-90 days of consistent use. We recommend a 90-day supply for the best results.
2. Will AlphaCleanse help with fatty liver?
AlphaCleanse is formulated to provide nutritional support for liver function. Many of our customers with fatty liver have reported improvements in their liver enzyme levels and overall well-being. However, we always recommend consulting with your healthcare provider for specific medical conditions.
3. I tried other liver supplements. Why is this different?
Most liver supplements contain only milk thistle, which supports Phase I detoxification. AlphaCleanse is a 12-ingredient formula covering Phase I, Phase II, and absorption. BioPerine (black pepper extract) increases bioavailability by up to 2,000%. No proprietary blends. Every ingredient and dose is listed on the label.
4. Can I take it with my current medications?
AlphaCleanse is made with organic plant-based ingredients. However, because it supports liver function (which processes medications), we strongly recommend consulting your doctor or pharmacist before adding any supplement to your regimen, especially if you take prescription medications.
"Is it safe and legitimate?"
5. What are the ingredients and doses?
Every ingredient and exact dose is listed on our label. No proprietary blends. The 12 ingredients include: Milk Thistle (165mg), Turmeric (110mg), Ginger (110mg), Spirulina (110mg), Dandelion Root (55mg), Reishi Mushroom (55mg), Beetroot (55mg), Schisandra Berry (27.5mg), Rhubarb Root (27.5mg), Burdock Root (27.5mg), Nettle Leaf (27.5mg), and BioPerine (2.75mg).
6. Any side effects?
AlphaCleanse is made with organic, plant-based ingredients and is generally well-tolerated. Some customers report mild digestive adjustment during the first few days as the formula begins to work. This typically resolves quickly. If you experience any discomfort, reduce to 1 capsule daily and gradually increase.
7. Is it made with organic ingredients?
Yes. AlphaCleanse is made with organic ingredients. The formula includes 11 plant-based ingredients plus BioPerine (black pepper extract), a patented, clinically studied extract that increases absorption of the other ingredients by up to 2,000%.
8. How do I know the reviews are real?
All 700+ reviews are collected and verified through Okendo, an independent third-party review platform. Every reviewer has a verified purchase badge. We do not edit, filter, or incentivize reviews. What you read is what real customers wrote.
"What about the money?"
9. How does the 60-day guarantee work?
Try AlphaCleanse for up to 60 days. If you are not satisfied for any reason, contact us for a full refund. No questions asked. No hoops. You can even keep the bottle. We take on all the risk because we are confident the product works.
10. What's the best value option?
The 3-bottle subscription is our best value at $39.20/bottle ($1.31/day). That is a 20% savings over the one-time price, plus you get a free Fatty Liver Guide. Most customers see the best results after 60-90 days, so a 3-bottle supply ensures you do not run out during the critical improvement window.
11. Can I cancel my subscription anytime?
Yes. You can cancel, pause, or modify your subscription at any time through your account dashboard or by contacting our support team. There are no contracts, no commitments, and no cancellation fees.
12. How long does shipping take?
All orders include free standard shipping, which typically arrives within 3-5 business days in the US. International shipping is available and usually takes 7-14 business days depending on your location. You will receive a tracking number via email once your order ships.
13. How is this different from a Facebook ad supplement?
We get it. Most supplement ads on Facebook are noise. Here is what makes this different: every ingredient and dose is on the label (no proprietary blends), all 700+ reviews are verified through Okendo (an independent platform), and we offer a 60-day money-back guarantee. No questions asked. If you are not satisfied for any reason, full refund.
27 PubMed-Cited References
  1. Abenavoli L, et al. Milk thistle in liver diseases: past, present, future. Phytother Res. 2010;24(10):1423-32.
  2. Saller R, et al. The use of silymarin in the treatment of liver diseases. Drugs. 2001;61(14):2035-63.
  3. Vargas-Mendoza N, et al. Hepatoprotective effect of silymarin. World J Hepatol. 2014;6(3):144-9.
  4. Clare BA, et al. The diuretic effect in human subjects of an extract of Taraxacum officinale folium. J Altern Complement Med. 2009;15(8):929-34.
  5. Gonzalez-Castejon M, et al. Diverse biological activities of dandelion. Nutr Rev. 2012;70(9):534-47.
  6. Panossian A, Wikman G. Pharmacology of Schisandra chinensis Bail.: an overview. Phytomedicine. 2008;15(6-7):433-45.
  7. Ip SP, et al. Effect of schisandrin B on hepatic glutathione antioxidant system. Planta Med. 2000;66(6):521-4.
  8. Wachtel-Galor S, et al. Ganoderma lucidum (Lingzhi or Reishi). In: Herbal Medicine. 2nd ed. CRC Press; 2011.
  9. Haniadka R, et al. A review of the gastroprotective effects of ginger. Food Funct. 2013;4(6):845-55.
  10. Prasad S, Aggarwal BB. Turmeric, the golden spice: from traditional medicine to modern medicine. In: Herbal Medicine. 2nd ed. CRC Press; 2011.
  11. Hewlings SJ, Kalman DS. Curcumin: A review of its effects on human health. Foods. 2017;6(10):92.
  12. Foerster B, et al. Rhubarb: chemistry and pharmacology. Phytochem Rev. 2015;14:165-86.
  13. Chan YS, et al. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-54.
  14. Deng R, Chow TJ. Hypolipidemic, antioxidant and anti-inflammatory activities of microalgae Spirulina. Cardiovasc Ther. 2010;28(4):e33-45.
  15. Fiedor J, Burda K. Potential role of carotenoids as antioxidants in human health and disease. Nutrients. 2014;6(2):466-88.
  16. Clifford T, et al. The potential benefits of red beetroot supplementation in health and disease. Nutrients. 2015;7(4):2801-22.
  17. Shokri Mashhadi N, et al. Anti-oxidative and anti-inflammatory effects of ginger in health and physical activity. Int J Prev Med. 2013;4(Suppl 1):S36-42.
  18. Upton R. Stinging nettles leaf (Urtica dioica L.): extraordinary vegetable medicine. J Herb Med. 2013;3(1):9-38.
  19. Shoba G, et al. Influence of piperine on the pharmacokinetics of curcumin. Planta Med. 1998;64(4):353-6.
  20. Badmaev V, et al. Piperine, an alkaloid derived from black pepper increases serum response of beta-carotene. Nutr Res. 1999;19(3):381-8.
  21. Suresh D, Srinivasan K. Tissue distribution and elimination of capsaicin, piperine and curcumin following oral intake. Indian J Med Res. 2010;131:682-91.
  22. Flora K, et al. Milk thistle (Silybum marianum) for the therapy of liver disease. Am J Gastroenterol. 1998;93(2):139-43.
  23. Post-White J, et al. Advances in the use of milk thistle. Integr Cancer Ther. 2007;6(2):104-9.
  24. Loguercio C, Festi D. Silybin and the liver: from basic research to clinical practice. World J Gastroenterol. 2011;17(18):2288-301.
  25. Mulrow C, et al. Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects. Evid Rep Technol Assess. 2000;(21):1-11.
  26. Rainone F. Milk thistle. Am Fam Physician. 2005;72(7):1285-8.
  27. Zhong S, et al. The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease. J Dig Dis. 2017;18(4):227-37.