In a 12-week study conducted by independent research lab Citruslabs, 40 adults aged 40–65 took AlphaCleanse daily. Here is what happened to their digestive comfort, energy, and liver-associated blood markers — reported exactly as measured.
Conducted by Citruslabs40 participants, ages 40–6512 weeksBlood-tested at baseline & week 12
−38.6%
Digestive symptom score (GSRS)
p<0.0001
−24.0%
Fatigue score (MFI)
p<0.0001
+31.1%
Improvement in energy-level rating
p<0.0001
−10.6%
Alkaline phosphatase (liver blood marker)
p=0.0145
Digestive & Fatigue Outcomes
Improvements that grew stronger every month
Two validated questionnaires — the Gastrointestinal Symptom Rating Scale (GSRS) and the Multidimensional Fatigue Inventory (MFI) — were completed at baseline, week 4, week 8, and week 12. On these scales a lower score means fewer symptoms or a better rating, so every result below is an improvement — and each was statistically significant versus baseline.
Digestive symptoms (GSRS)
36.6 at baseline → 22.4 at week 12 · improving from week 4 (−26.6%) through week 12
−38.6%p<0.0001
Fatigue (MFI)
59.1 at baseline → 44.9 at week 12
−24.0%p<0.0001
Feeling run-down or sick
How often, over the prior 4 weeks
−36.8%p<0.0001
Overall energy-level rating
Self-rated · improved from 3.4 to 2.3 (on a scale where a lower score means better energy)
+31.1%improved · p<0.0001
Disrupted or difficult sleep
How often, over the prior 4 weeks
−30.5%p<0.0001
Daytime tiredness or sleepiness
How often, over the prior 4 weeks
−27.9%p<0.0001
Liver-Associated Blood Marker
A measurable change in the bloodwork
Participants were blood-tested at baseline and week 12. A statistically significant improvement was observed in alkaline phosphatase — a blood marker associated with liver health — which fell from an average of 86.6 to 77.4 IU/L. Other liver markers (ALT, AST, albumin, bilirubin) did not change significantly over the 12 weeks.
Alkaline phosphatase (ALP)
86.6 → 77.4 IU/L average, baseline to week 12
−10.6%p=0.0145
In Participants' Own Words
What people reported by week 12
At week 12, participants rated their own experience. Figures show the percentage who agreed or strongly agreed with each statement — these are self-reported perceptions, not clinical measurements.
9 of 11product-experience statements reached ≥50% agreement by week 12
Experienced less bloating75.7%
Would like to keep using it75.7%
Would recommend to family & friends73.0%
More regular bowel movements70.3%
Improved digestive comfort62.2%
Feel physically fitter59.5%
Feel less sluggish56.8%
Overall health improved56.8%
Feel less irritable54.1%
Energy levels increased51.4%
How the Study Was Run
Independent, structured, and transparent
40
Adults aged 40–65 reporting low energy, fatigue, and digestive symptoms
12 wk
Daily use — two capsules once a day with the first meal
Blood panels at baseline and week 12 (ALT, AST, ALP, albumin, bilirubin)
The study was designed, run, and analyzed by Citruslabs, an independent clinical research organization. It was a single-arm study (all participants took AlphaCleanse; there was no placebo group). Analyses used GraphPad Prism with significance set at p<0.05.
Feel the difference for yourself
AlphaCleanse is made with milk thistle, spirulina, ginger, and turmeric to support healthy liver and digestive function.
